GTR3 is Waves' take on amp simulation and effects and they say that they have "Captured the world's hottest vintage and contemporary amps, using revolutionary sampling techniques that go way beyond standard modeling." GTR3 has had input from guitar maker Paul Reed Smith who has contributed custom settings and you can, in fact, buy a version of GTR3 with a hardware PRS interface that transforms your unbalanced high impedance guitar signal into a balanced low impedance signal, reducing hum and retaining your full dynamic range.
Mac and PC
Standalone, TDM, VST, Audio Units
Pricing and Availability: $140 MSRP (software) $199 MSRP (software with PRS hardware)