The S-50 was one of the first affordable (?) 16-bit samplers. Of course 750 KB sample memory isn't a lot by todays standards, but the S-50 together with an extern CRT-screen and digitizer tablet - besides from looking real awesome - allowed a lot of cool things to be achieved. The S-50 is a breeze to use, and the sampling quality is nice and free from distortion, even if the bandwidth is somewhat crippled (due to the 30KHz sampling frequency).
Comments About the Sounds:
It's a 16-bit sampler, but the samples are internally processed as 12-bit data. Nice and clean, but somewhat muffled (15 KHz filtering).